Peptide Blend
Ipamorelin + CJC-1295
Ipamorelin: A selective growth hormone secretagogue (GHRP) that mimics ghrelin to stimulate natural, pulsatile GH release from the pituitary with minimal impact on cortisol or prolactin. Researched for improved body composition (muscle gain, fat loss), recovery, sleep, and anti-aging effects.
CJC-1295: A long-acting analog of growth hormone-releasing hormone (GHRH). Stimulates the pituitary gland to increase endogenous GH and IGF-1 levels in a sustained, pulsatile manner. Researched for improving body composition, recovery, muscle growth, fat metabolism, and anti-aging effects.
Together, Ipamorelin and CJC-1295 work synergistically — GHRP and GHRH acting on complementary pathways for amplified, selective GH release.
Overview
This blend pairs Ipamorelin — a selective growth hormone releasing peptide (GHRP) and ghrelin mimetic — with CJC-1295, a synthetic GHRH analogue. The two peptides operate through distinct but complementary receptor systems: CJC-1295 engages pituitary GHRH receptors to stimulate GH production, while Ipamorelin binds ghrelin/GHS-R1a receptors to amplify the GH pulse and suppress somatostatin, the endogenous GH inhibitor.
This dual-pathway approach is studied for its potential to generate a more robust, physiologically patterned GH secretion event compared to either peptide alone, while maintaining the selectivity profile that makes Ipamorelin notable — minimal effects on cortisol, prolactin, or ACTH at research-relevant concentrations.
Research Highlights
Research involving the Ipamorelin + CJC-1295 combination has explored its effects on lean body mass accrual, adipose tissue mobilization, sleep quality improvement (via GH pulse timing), immune system modulation, and recovery from exercise-induced muscle damage. Studies have also investigated its potential to elevate systemic IGF-1 levels, which mediates many of the anabolic and repair-associated effects downstream of GH axis activation.
The selectivity of ipamorelin — producing GH release without proportional ACTH/cortisol co-stimulation — is a particular focus in studies comparing GHRP selectivity across peptides in this class. The combination is widely referenced in growth hormone axis research for its mechanistic clarity and relative receptor specificity.
For research use only. Not intended for human consumption.
Specifications
| Components | Ipamorelin (10mg) + CJC-1295 w/o DAC (10mg) |
| CJC-1295 Formula | C₁₅₂H₂₅₂N₄₄O₄₂ · MW 3,367.896 g/mol · CAS 863288-34-0 |
| Purity | ≥99% (HPLC verified, each component) |
| Form | Lyophilized powder |
| Storage | −20°C. Stable ≥24 months lyophilized. |
| Origin | USA |
Certificate of Analysis
Each batch is independently tested by a third-party laboratory. A Certificate of Analysis (COA) confirming purity and identity is available upon request. Contact us with your order number to receive the COA for your specific lot.