Research Peptide
BPC-157
A stable gastric pentadecapeptide derived from a protective protein in stomach juice. Promotes tissue healing and repair — tendons, ligaments, muscles, bones, and gut — by enhancing blood vessel formation, reducing inflammation, supporting fibroblast activity, and modulating nitric oxide and dopamine systems. Researched for injury recovery, GI protection, and anti-inflammatory effects.
Overview
BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide derived from a naturally occurring protective protein found in human gastric juice. Its 15-amino-acid sequence — Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val — has been the subject of extensive preclinical investigation for its regenerative capacity across a broad range of tissue types.
Mechanistically, BPC-157 is believed to promote angiogenesis through upregulation of VEGFR2 signaling, stimulate nitric oxide synthesis, and modulate growth hormone receptor pathways. These actions are hypothesized to collectively drive the accelerated healing responses observed in animal models involving tendon, ligament, muscle, bone, and gastrointestinal tissue.
Research Highlights
Preclinical studies in rodent models have documented BPC-157's ability to markedly accelerate the healing of Achilles tendon transections and medial collateral ligament injuries, with researchers noting enhanced collagen deposition and improved tensile strength at the injury site compared to control groups.
Additional lines of inquiry have explored its gastroprotective effects — particularly its capacity to attenuate NSAID-induced gastric lesions and support intestinal epithelial repair — as well as neuroprotective activity in models of traumatic brain injury and dopaminergic dysfunction. It has also been studied for its systemic anti-inflammatory properties and its interaction with the serotonin and dopamine neurotransmitter systems.
For research use only. Not intended for human consumption.
Specifications
| Sequence | Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val |
| Molecular Weight | 1,419.54 g/mol |
| Chemical Formula | C₆₂H₉₈N₁₆O₂₂ |
| CAS Number | 137525-51-0 |
| PubChem CID | 9941957 |
| Purity | ≥99% (HPLC verified) |
| Form | Lyophilized powder |
| Storage | −20°C. Stable ≥24 months lyophilized. |
| Origin | USA |
Certificate of Analysis
Each batch is independently tested by a third-party laboratory. A Certificate of Analysis (COA) confirming purity and identity is available upon request. Contact us with your order number to receive the COA for your specific lot.